I have two "main" character archetypes.
Jeff
Alignment - Neutral Good [Generally Neutral, anyway]
Basically me. I try to do what's best for the people around me, don't generally steal, and only ever murder people if I feel they really, really deserve it. Except for my first playthrough of Fallout 3 where I murdered silver and then instantly felt extremely disgusted with myself and guilty. (Though not enough to load a previous save - I should get back into the non-habit of doing that.) This sometimes leads to situations like getting the Ghouls in west DC to peacefully move into Tenpenny tower, and then having to bring justice to them later on when they slaughter everyone. Whoops.
I tend to favour heavy armour, conventional ranged weapons, and a wee bit of stealth.
[Name Not Consistent
Chaotic Evil
Female, usually redhead, psychopathic. She doesn't always murder people, but when she does, it's usually because she felt like it, rather than a legitimate reason. Stealing is, of course, always an option, as is trickery. Often employs stealth, unless she's making a ruckus for the sheer fun of it. May or may not side with the "bad guys" when the option is given.
Nick
Lawful Good(ish)
This isn't a standard character by any means, but I like to tell the story.
Nick (named after the recently-transferred CSI character, because Vegas) was my attempt at a cowboy build in New Vegas, as something new do try. I was also trying some new mods to make things a bit less forgiving. The net result of this was that shortly after passing through Primm, I was ambushed by some powder gangers, blown the heck up, and, due to lack of doctor's bags in my inventory or anywhere between Primm and there, I had to limp, crying and bleeding, with my right arm busted up, the entire way through Nipton into Novac.
Was quite invigorating, and also a very large relief when I finally got to Novac's quack doctor to set my broken bones.
On subsequent a playthrough with my "Me" character, I also had a mod that adds lens overlay effects while wearing headgear, which had the effect of me having to go on a desperate search through various ruins for the first 4 hours of the game or so to find parts to repair my cracked prescription lenses so I could actually goddamn see. I really like experiences like that in my games - small, self generated quests made by various game systems interacting together in a way that nobody explicitly intended.