We could....
Make a map based of off a movie (ex. James Bond, Fifth Element) and have all the main scenes in the movie included! The more action the better.
or...
Map something strange, have a really odd effect. Or something that would utterly confuse a player.
Or maybe even...
Do a Mcguyver (don't know how to spell his name) where you need to get to (A) by combining (B) with (C) so that (D) will do something so you can get from (E) to (A). More or less a real complicated puzzle in one room.
Just a few suggestions