Archie is the man to ask about lighting stuff, but trippy stuff, you might be better off asking zeeba-g and/or checking out some of his somewhere in time dream map, which is full of trippy lighting.
This is for goldsurce, correct? If yes, maybe start experimenting with some static texture lights if you aren't already. (texture lights are the shizzle in goldsoure for lighting if you didn't know already)
There are all sorts of things you can entity lighting(light, light_spot) for special effects with pulses and strobes and such. maybe set up a test map with a doezen light entities with different render properties to see what you can do.
You can also use tricks to accent your lighting using FADE texture and volumentric light can really add some cool effects to light fixtures, as well env_sprites of course.
Hopefully this helps a little, and other's share their ideas