Ill want mass effect 2 as well. The first would've been great if the planet exploration wasn't so douchy, and if the fighting system had a little bit more feel to it. With all of the reviews which said just that, surely they will fix it.
There's also Assassins Creed 2. They havn't released any game footage yet, so im excited. Maybe there will be more to do in between missions, heh. I have read that the main guy can swim now, so that's cool.
I do also want BG&E2, SC2, more stuff on Diablo 3, a new zelda, golden sun three (I never heard anything about it), and to a much lesser extent Lost Planet 2.
Its almost time for another Splinter Cell too.. by the good ubisoft team that makes them and not the people that did Double Agent. Its the CT people.